Myristyl myristate is most often made from vegetable oils for cosmetic use. 77, is. It is a lightweight emollient commonly used to make formulations feel less greasy. . From the available information, it is concluded that Myristyl Myristate and Isopropyl Myristate are safe as cosmetic ingredients in the present practices of use. David Ruskin. Keep an eye on:Nothing to keep an eye on here, myristyl myristate is safe and doesnt cause irritation. Isopropyl Myristate only exists as a refined product. From the available information, it is concluded that Myristyl Myristate and Isopropyl Myristate are safe as cosmetic ingredients in the present practices of use. Isopropyl myristate is easily penetrated into the skin whereas the petrochemicals get clogged in pores leading to a decline in supply of oxygen to the skin resulting in several skin related issues. Myristyl myristate is the ester of the fatty alcohol myristyl alcohol and fatty acid myristic acid. In certain soap formulations, an excess of myristyl myristate produces pearl effects giving the skin a glossy appearance. Category. According to research conducted by the Cosmetic Ingredient Review Expert Panel, it is safe for its indicated use. 10, is. StabilizerMyristyl myristate is also used for its stabilizing benefits. It's particularly good at reducing the greasy feel caused by high oil content in a product, and it's generally considered to be safe. Studies with rabbits indicated that undiluted It is an ester that combines alcohol and fatty acids. In cosmetics and personal care products, Isopropyl Myristate functions as a binder, and skin-conditioning agent emollient. stearic acid . The combination of fatty alcohol and fatty acids thickens emulsions and . Isopropyl Myristate is an ester of isopropyl alcohol (aka rubbing alcohol) and myristic acid (a fatty acid that naturally occurs in coconut and palm oils). Laureth-4. Keep an eye on: As isopropyl myristate helps ingredients to penetrate the skin, it is important, especially for sensitive skin types, that you assess the other ingredients in your product. Isopropyl myristate has three main benefits for the scalp and hair. Myristyl myristate reduces the watery feel of hand and body lotions and imparts a richness in the sensory feel of the products. Interestingly, the addition of myristyl myristate to an emulsion can take it from dull gray to bright white, making the product look more appealing. Hello. . Both isopropyl myristate and isopropyl palmitate are ester compounds. Solubility: Insoluble in Water. References: Brinkmann, I & Mller-Goymann, C, 2003. Final Report on the Safety Assessment of Myristyl Myristate and Isopropyl Myristate, International Journal of Toxicology, vol.1. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. 2017;1859(5):745-755. doi:10.1016/j.bbamem.2017.01.029, Czarnowicki T, Malajian D, Khattri S, et al. Isopropyl Myristate is also a great lightweight emollient; you can include it in recipes as an alternative to a liquid carrier oil to make for a lighter, faster-absorbing product. . She covers all things skincare for Byrdie, from ingredients to acne advice. 1, pp. Is isopropyl myristate toxic? The good: Isopropyl myristate works as an emollient, helping to maintain the skins natural barrier and retain moisture. Texture. 96-105. Cosmeticsinfo.org. 214-223 Cosmetic Ingredient Review, 1982. Palep recommends this eye cream for retinol newbies, since it's gentle yet still works. The following functions have been reported for Myristic Acid and its salts and esters. 270.5. Nonetheless, isopropyl myristate is not considered to be . Myristic Acid is a saturated fatty acid with 14 carbon atoms. In cosmetics and skincare products, myristyl myristate functions as an emollient, texture enhancer, and moisturizer. Isopropyl myristate is sometimes used as an artificial flavor in food. Best Skin Whitening Lightening Creams 2022, What Are The Benefits of Isopropyl Myristate, Difference Between Humectant, Emollient, Occlusive, Everything You Need to Know About Peptides. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. Dry to normal skin types will benefit most from the moisture-locking abilities. Interestingly, the addition of myristyl myristate to an emulsion can take it from dull gray to bright white, making the product look more appealing. 1 shows the results. While there are plenty of emollients on the market, isopropyl myristate has the added benefit of enhancing the penetration of other ingredients (more on that below). And, as with any other ingredients and products, you should patch test in case of an allergy. IUPAC Name. Comedogenicity of current therapeutic products, cosmetics, and ingredients in the rabbit ear, Journal of the American Academy of Dermatology, vol. 393-404. Cos White Diamond: is a COSMOS-approved and patented, 100% opacifying, whitening and filling agent. Mineral oil is a laxative and eye irritant and has an oral LD50 of 22 g/kg (mouse). Isopropyl myristate can help to improve the texture of the products. Based on these findings, the CIR Expert Panel concluded that myristic acid and its salts and esters were safe as a cosmetic ingredient when its used for its approved uses and concentrations. As an emollient myristyl myristate works to soften and soothe the skin and hair. This action helps to trap water in the top few layers of the skin, improving the skin barrier integrity. Myristyl myristate is generally used as an emollient, texture enhancer, and co-emulsifier. Read our, The Best Products With Isopropyl Myristate, Intensive Care Cocoa Radiant Spray Moisturizer. Isopropyl Myristate is an ester of the fatty acid Myristic Acid. Rather than increasing the amount of emulsifier, which would stiffen the product, a co-emulsifier like myristyl myristate can be used to improve the overall emulsion stability while delivering additional benefits not offered through increased emulsifiers. 214-223 Cosmetic Ingredient Review, 1982. Designed by Elegant Themes | Powered by WordPress, You'll need to upload them to a free image hosting service first, Sodium (C14-16) alpha olefin sulfonate (Bio-Terge AS40), How to add actives and other ingredients to your lotions. ISOPROPYL MYRISTATE: Isopropyl Myristate made from the combination of isopropyl alcohol and the naturally derived fatty acid myristic acid. Isopropyl myristate was varied in each formulation to be 32%, 28%, and 23%, respectively and oleic acid was varied in each formulation to be 13%, 8%, and 3%, respectively. The first component is isopropyl alcohol, the antimicrobial agent used in some hand sanitizers, baby wipes, and antiseptic formulations. This cosmetic ingredient produced minimal to mild skin irritation, minimal eye irritation in rabbits, and no sensitization in guinea pigs. Isopropyl Myristate (IPM) is an ester of isopropyl alcohol and myristic acid (a fatty acid that naturally occurs in coconut and palm oils). C17H34O2. Disruption of the skins natural barrier has been linked to skin conditions such as eczema, so skin barrier health is vital to clear healthy-looking skin. In formulation, it prevents oil-based ingredients from feeling too greasy or heavy but creating an even emulsion. A synthetic oil, isopropyl myristate is made up of isopropyl alcohola propane derivativeand myristic acid, a naturally-occurring fatty acid, explains Palep. Myristyl myristate is a naturally derived fatty alcohol. 16, pp. The skin barrier is the first few layers of the skin and the natural oils that the skin produces that protect the skin from bacteria, allergens, and prevents water loss to the environment. Common Uses: Lotions. The highest naproxen permeability was afforded by IPM (36.2 x 10(-4) cm h-1), followed by menthol (25.0 x 10(-4) cm h-1), oleic acid (11.1 x CIR Safety Review: The CIR Expert Panel recognizes that the salts of Myristic Acid dissociate to form Myristic Acid and esters of Myristic Acid are hydrolyzed to their corresponding alcohols and Myristic Acid which are then further metabolized. Every product and ingredient in Skin Deep gets a two-part score - one for hazard and one for data availability. 14. Myristyl Myristate acts as an emulsifier and emollient in lotion formulations. The oil possesses a number of unique characteristics that make it a valuable additive in numerous . Isopropyl myristate is one of only five ingredients in this serum. The safest products score well by both measures, with a low hazard rating and . Hand sanitizers using active ingredients other than alcohol (ethanol), isopropyl alcohol, or benzalkonium chloride are not legally marketed, and FDA recommends that consumers avoid their use. N. Myristyl myristate reduces the watery feel of hand and body lotions and imparts a richness in the sensory feel of the products. Isopropyl Myristate USP helps gives a silky smooth and velvet texture when making cosmetics such as personal skin care products. Include it in the oil phase of your products; it can be hot or cold processed. What are the Best Skin Care Products of 2022? These are organic compounds which can be categorized as fatty acids; they contain a . Isopropyl Myristate is included in formulas to dramatically reduce the greasy/oily feel; its brilliant in recipes with large amounts of butters that are famous for a heavier skin feel (like shea). Melt Point: 100.4 F. It is an exceptionally lightweight emollient and can be utilized like a transporter oil in numerous applications. Myristic Acid, also called tetradecanoic acid, occurs naturally in vegetable or animal fats and oils with relatively high levels found in nutmeg, palm oil, coconut oil and butter fat. Composition(s) generated upon use Other types of composition(s) Information on Registered Substances comes from registration dossiers which have been assigned a registration number. It leaves a smooth satiny after feel. myristyl myristate. Based on the structural similarities of these compounds, and the knowledge that in the body similar metabolites are formed, the CIR Expert Panel concluded that Myristic Acid, Aluminum Dimyristate, Aluminum Isostearates/Myristate, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Potassium Myristate, Sodium Myristate, Zinc Myristate, Butyl Myristate, Cetyl Myristate, Decyl Myristate, Ethylhexyl Myristate, Ethyl Myristate, Glyceryl Dimyristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Isobutyl Myristate, Isocetyl Myristate, Isodecyl Myristate, Isopropyl Myristate, Isostearyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Methyl Myristate, Myristyl Myristate, Octyldodecyl Myristate, Oleyl Myristate, Propylene Glycol Myristate, Tetradecyloctadecyl Myristate and Tridecyl Myristate were safe as a cosmetic ingredient in the present practices of use and concentration. The key difference between isopropyl myristate and isopropyl palmitate is that isopropyl myristate is the ester of isopropyl alcohol and myristic acid whereas isopropyl palmitate is the ester of isopropyl alcohol and palmitic acid.. Ethyl Myristate, Glyceryl Myristate and Isopropyl Myristate were not sensitizers. She is currently a Cosmetic and Laser Fellow at Harvard Massachusetts General Hospital. An antiperspirant and/or deodorant stick composition is disclosed comprising (a) 10-60 weight % of a volatile silicone such as cyclomethicone; (b) 2-30 weight % of a low melting point wax gelling agent (particularly stearyl alcohol); (c) 1-10 weight % of a high melting point wax (such as hydrogenated castor oil); (d) 0-15 weight % of an emollient which is different from (b) and (c); (e) 0.1-10 . Myristyl myristate | C28H56O2 | CID 18605 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . The esters of Myristic Acid are derived from Myristic Acid and an alcohol. In certain soap formulations, an excess of myristyl myristate produces pearl effects giving the skin a glossy appearance. Both animal and human studies have demonstrated that myristyl myristate does not produce skin irritation or sensitization. DPG is far more volatile than IPM, which as another poster says, doesn't evaporate. The result is a highly versatile cosmetic ingredient that works to enhance texture, improve spreadability, add opacity to creams, serums and lotions, offer skin-softening emollient properties, and offer a non-greasy occlusive finish that helps prevent dehydration. It gives body and consistency to the formula and leaves a velvety feel on the skin. Uses. Biochim Biophys Acta Biomembr. The Skin Deep scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern. Among the salts and esters of Myristic Acid that may be used in cosmetics and personal care products, Isopropyl Myristate is most likely to be used. Myristyl Myristate is most commonly used to improve the performance of emulsions. Studies with rabbits indicated . Isopropyl Myristate is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products. Following oral exposure, Butyl Myristate and Ethyl Myristate were not toxic. Myristic acid is most commonly used in eye makeup, moisturizers, soaps and detergents, hair care products, nail care products, shaving products, and other skincare products. Molecular Formula. Myristyl myristate exists as a white or yellowish waxy solid. Does isopropyl myristate clog pores? FDA Code of Federal Regulations for fatty acids Myristic Acid and its salts and esters may be used in cosmetics and personal care products in Europe according to the general provisions of the Cosmetics Directive of the European Union. Products with isopropyl myristate help to create a protective coating on the surface of the skin. You could try something like isododecane or cyclomethicone, but ingredients like that are very volatile, meaning they cannot be heated much and will evaporate out of the finished product over time if given the opportunity. The safety of Myristic Acid and its salts and esters (Aluminum Dimyristate, Aluminum Isostearates/Myristate, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Potassium Myristate, Sodium Myristate, Zinc Myristate, Butyl Myristate, Cetyl Myristate, Decyl Myristate, Ethylhexyl Myristate, Ethyl Myristate, Glyceryl Dimyristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Isobutyl Myristate, Isocetyl Myristate, Isodecyl Myristate, Isopropyl Myristate, Isostearyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Methyl Myristate, Myristyl Myristate, Octyldodecyl Myristate, Oleyl Myristate, Propylene Glycol Myristate, Tetradecyloctadecyl Myristate, Tridecyl Myristate) has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel.
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